庞景灼,巫国勇,叶敏,庞文广,张世超,蔡成杰Vol.41(6):- 摘要:应用血栓弹力图(TEG)检测食管癌患者围手术期各个阶段的凝血功能,了解食管癌围手术期凝血功能的变化规律。指导术后抗凝或止血治疗。选取年5月至年5月医院确诊为食管癌并行手术治疗的60例患者为手术组,另选取60例健康体检者为正常对照组,通过对正常对照组、手术组术前1d、术后第1天、术后第7天的血标本进行血栓弹力图检测,分析食管癌围手术期凝血功能的变化。手术组术前和正常对照组比较,TEG参数R、K、LY30值减小,Angle、MA、CI值增大,差异有统计学意义(P0.05)。手术组术后1天和正常对照组比较,TEG参数R、K值明显减小,Angle、MA、CI值明显增大,差异有统计学意义(P0.01),LY30值减小,差异有统计学意义(P0.05)。手术组术后1d和手术组术前1d比较,TEG参数R、K值减小,LY30、Angle、MA、CI值增大,差异无统计学意义(P0.05)。手术组术后7d和术后1d比较,TEG参数R、K值减小,MA、CI值增大,差异有统计学意义(P0.05)。食管癌患者术前、术后均表现为高凝状态。手术和麻醉并没有明显改变食管癌的凝血状态。在术后恢复过程中,血液高凝状态会更明显。 关键词:食管癌;血栓弹力图;高凝状态 Abstract:Thrombelastogram(TEG)wasusedtodetectthebloodclottingfunctionofpatientswithesophagealcancerineachstageofperioperativeperiod,soastounderstandthechangepatternofbloodclottingfunctioninpatientswithesophagealcancerduringperioperativeperiod,andtoguidethepostoperativeanticoagulationorhemostasistreatment.SixtypatientsdiagnosedwithesophagealcancerwhounderwentsurgicaltreatmentbetweenMayandMayinJiangmenCentralHospitalwereselectedastheexperimentalgroup,and60casesofhealthyphysicalexaminationwereselectedasthenormalcontrolgroup.Bycontrastingwiththenormalcontrolgroup,resultsofbloodsampletestingfortheexperimentalgroup1daybefore,1dayafteroperation,andthe7thdaypostoperativethrombosiselasticfigurewereusedtoanalyzethechangeoftheesophagealperioperativebloodcoagulationfunction.Comparedwiththecontrolgroupbeforesurgery,theTEGparametersR,KandLY30decreased,andAngle,MAandCIincreased,withstatisticallysignificantdifferences(P0.05).Comparedwiththenormalcontrolgroupaftersurgery,theRandKvaluesofTEGparametersintheexperimentalgroupdecreasedsignificantly,whileAngle,MAandCIvaluesincreasedsignificantly,withstatisticallysignificantdifferences(P0.01),andLY30valuesdecreased,withstatisticallysignificantdifferences(P0.05).Comparedwiththeexperimentalgroupbeforeandaftersurgery,theTEGparametersRandKdecreased,andthevaluesofLY30,Angle,MAandCIincreased,withnostatisticallysignificantdifference(P0.05).Sevendaysaftertheoperationand1dayaftertheoperation,thevaluesofRandKofTEGdecreased,andthevaluesofMAandCIincreased,withstatisticallysignificantdifferences(P0.05).Allpatientswithesophagealcancerpresentedhypercoagulabilitybeforeandafteroperation.Surgeryandanesthesiadidnotsignificantlychangethecoagulationstatusofesophagealcancer.Inthepostoperativerecoveryprocess,thehypercoagulablestatewillbemoreobvious. Keywords:esophagealcancer;thrombelastogram;hypercoagulability 编辑:王清波 初审:祁方昉 复审:孙慧兰余菁 审核发布:徐杰 预览时标签不可点收录于话题#个上一篇下一篇转载请注明原文网址:http://www.hbkje.com/jbyw/3996869.html |